Bobby Riehle

Bobby Riehle

E-mail: riehle.r@husky.neu.edu
Department: Pharmaceutical Sciences
Advisor: Vladimir Torchilin

Biography

I graduated from NC State University with a BS in Polymer Chemistry. An interest in pharmaceutical sciences and knowledge of medical applications of polymers lead me to pursue a PhD in Pharmaceutics and Drug Delivery in the Department of Pharmaceutical Sciences at Northeastern University in 2008.The IGERT program was an opportunity for me to look beyond the scope of my own research field and see how other research disciplines look at Nanotechnology and Nanomedicine in particular. My research interests were primarily in the area of utilizing nanoparticles to overcome barriers to drug delivery and treatment. Following acceptance into the program I was fortunate enough to be able to attend several interesting conferences and talks that I would not have been able to otherwise. I am also able to interact and exchange ideas with other students in different fields.I am working on several projects currently. The main project is the development of a micelle drug delivery system combining a novel chemotherapeutic incorporated into the nanoparticle with an apoptosis inducing protein on the surface. I am also working on dual-targeted gene delivery liposomes with Folic Acid and Transferrin targeting agents conjugated to the surface. Lastly, I am working with collaborators at Tufts University on incorporating pro-apoptotic peptides into liposomes in order to increase cellular uptake and cancer cell death.Through the IGERT program I have had the ability to travel to conferences in Washington DC, Raleigh, NC and an upcoming conference in Quebec City. I have also had the opportunity to volunteer with several organizations throughout Boston educating young students on Nanomedicine.

**Graduated from NC State University (2007) with a BS in Polymer and Color Chemistry**

**Member AAPS**

**Member CRS**

Projects

• Development of Dual-Targeted Liposomes for Delivery of Nucleic Acid
• Combination Anticancer Nanopreparations of Novel Proapoptotic Drugs, TRAIL Ligand and siRNA
• Liposomal Loading and Delivery of Proapoptotic BH3 Peptides

Presentations

• Combination anticancer nanopreparations of novel proapoptotic drugs and TRAIL ligand, Riehle RD, NCI CCNE Principle Investigators Meeting (Boston MA), Sep 2011
• Dual Targeted Liposomes: Utilizing Folate and Transferrin for Increased Nucleic Acid Delivery, Riehle RD, Graduate Research Association of Students in Pharmacy (Boston, MA), Jun 2011
• Project 1: Combination Anticancer Nanopreparations of Novel Proapoptotic Drugs with TRAIL Ligand, Riehle RD, NCI Site Visit Northeastern University, Boston, MA