High-Throughput Microfluidic Platform for Personalized Nanomedicine

Student: Masoud Khabiry
Department: Bioengineering
Advisor: Nader Jalili

Abstract

Cancer remains as one of the leading causes of mortality worldwide, affecting over 10 million new patients every year. High-throughput studies of drug-loaded nanoparticles on patient derived cancer cells can be carried out in a novel and simple shear protected microfluidic platform. The goal of this proposal is to develop an integrated microfluidic system containing cell immobilization microchambers which enables the control of fluid flow, generates stable concentration gradients, and regulates cell-drug loaded nanoparticle interaction in a temporal and spatial manner.